Spravato (Esketemine) Therapy
Rapid relief for treatment-resistant depression when traditional
antidepressants haven’t worked
About Spravato Therapy
Spravato® is an FDA-approved nasal spray that offers a breakthrough approach to treating depression that hasn’t responded to traditional medications. Unlike conventional antidepressants that can take weeks or months to work, many patients experience improvement with Spravato® within hours or days. It’s the first and only FDA-approved treatment that targets your brain’s glutamate system, offering new hope when other antidepressants have fallen short.
The team at Beautiful Minds has experience administering Spravato® in our comfortable, supervised clinical setting. We’ve helped numerous patients find hope and healing when other treatments have fallen short.
Is Spravato® Right for You?
Spravato treatment may be an option if you…
Struggle with Treatment-resistant depression, depression that does not respond to two or more antidepressant medications.
Struggle with major depressive disorder accompanied by suicidal thoughts or behaviors.
Have experienced less than 50% improvement in your depression symptoms with previous medications
How Does It Work?
Spravato® works completely differently than traditional antidepressants. While most antidepressants adjust serotonin levels, Spravato® targets the brain’s glutamate system—your brain’s most abundant neurotransmitter network. This unique approach rapidly creates new neural connections, helping restore healthy brain communication patterns that lead to improved mood and mental clarity. It’s used alongside your current antidepressant for enhanced, comprehensive treatment.
The Spravato Treatment Process
Spravato is administered as a nasal spray in our under
the supervision of a physician
Treatment Schedule
Spravato is administered twice weekly for the first month, then reduced frequency based on your progress.
Treatment Session
Each visit takes 2-3 hours total. You can spend time in our designated quiet space relaxing, listening to music, or laying down. We monitor your response to ensure your safety and well-being
Ongoing care
After the first month, weekly treatments are recommended for 4 weeks. We discuss your progress and create a personalized schedule for maintence
Resources to Learn More
Below are some resources about the effectiveness of esketamine in treating depression.
- National Library of Medicine, “Esketamine for Treatment‑Resistant Depression: A Review of Clinical Evidence”
- Science Direct, “A Real-World Study Examining the Impact of Esketamine Nasal Spray in People Living with Major Depressive Disorder in Australia and New Zealand”
- Spravato, Patient Stories
Insurance Coverage For Spravato
If you are diagnosed with treatment-resistant depression and meet the following criteria,
then insurance may cover your Spravato treatment if you have previously tried 2
antidepressants, without success.
We review your insurance information to see if you are covered.
If you’re eligible, we take care of the entire approval process. All you have to do is give us a call.
Begin Your Journey
Request an appointment and our team will help you find your best treatment options.